Research

Below is information that supports the use of rTMS for treating depression, anxiety, OCD, chronic pain, and PTSD. The information includes research highlights, publications, and clinical trials, and is from experts in the field.

Research

  • Consensus Recommendations for the Clinical Application of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Depression 
    • Provides a set of recommendations for the clinical use of rTMS in treating depression. The recommendations are based on a consensus among a group of experts in the field who reviewed the available evidence and clinical experience with rTMS
    • https://pubmed.ncbi.nlm.nih.gov/28541649/
  • A meta-analysis of repetitive transcranial magnetic stimulation in the treatment of depression
    • This study reviews multiple randomized controlled trials and concludes that rTMS is a safe and effective treatment for depression. The study also explores different rTMS parameters and compares the effectiveness of rTMS with other treatments such as antidepressant medications and electroconvulsive therapy
    • https://www.ncbi.nlm.nih.gov/books/NBK68734/
  • Repetitive Transcranial Magnetic Stimulation for Generalized Anxiety Disorder: A Systematic Literature Review and Meta-Analysis
  • Efficacy and safety of repetitive transcranial magnetic stimulation for generalised anxiety disorder: A meta-analysis
    • This study aims to provide clinicians and patients with evidence-based information regarding the potential benefits and risks of using rTMS to treat GAD, which may inform treatment decisions and improve patient outcomes.
    • https://pubmed.ncbi.nlm.nih.gov/31673675/
  • The Value of Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Anxiety Disorders: An Integrative Review
    • The study aims to answer several research questions related to the potential benefits of rTMS for anxiety disorders, such as the effectiveness of rTMS in reducing anxiety symptoms, the potential mechanisms underlying its therapeutic effects, and the optimal parameters for rTMS administration
    • https://pubmed.ncbi.nlm.nih.gov/21631403/
  • For Obessive compulsive disorder (OCD):
    • Efficacy and tolerability of repetitive transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder in adults: a systematic review and network meta-analysis
      • The study aims to compare the efficacy of different rTMS protocols for OCD, including high-frequency rTMS, low-frequency rTMS, and theta-burst stimulation, as well as to evaluate their tolerability and safety
      • https://www.nature.com/articles/s41398-021-01453-0
    • Efficacy and Safety of Deep Transcranial Magnetic Stimulation for Obsessive-Compulsive Disorder: A Prospective Multicenter Randomized Double-Blind Placebo-Controlled Trial
      • Evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) as a treatment for obsessive-compulsive disorder (OCD) by conducting an exploratory meta-analysis of randomized and sham-controlled trials.
      • https://pubmed.ncbi.nlm.nih.gov/23615189/
  • New updates on transcranial magnetic stimulation in chronic pain
    • Explore how TMS affects pain perception by investigating its impact on the central nervous system and cortical excitability. It also reviews the current evidence on the effectiveness of TMS in treating different types of chronic pain, such as neuropathic pain, fibromyalgia, and migraine
    • https://pubmed.ncbi.nlm.nih.gov/35639571/
  • Recent advances in the treatment of chronic pain with non-invasive brain stimulation techniques
    • Non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) are being studied as potential treatments for chronic pain, with the goal of improving patients' quality of life and reducing healthcare costs associated with pain management
    • https://www.sciencedirect.com/science/article/abs/pii/
      S1474442207700327
  • Non-invasive brain stimulation for posttraumatic stress disorder: a systematic review and meta-analysis
        • Studies to determine the effectiveness of non-invasive brain stimulation techniques for the treatment of posttraumatic stress disorder (PTSD), compare the efficacy of different techniques, and identify areas for future research.
        • https://pubmed.ncbi.nlm.nih.gov/32467579/
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